Wim Floren

JNJ-26481585, a Novel Second-Generation Oral Histone Deacetylase Inhibitor, Shows Broad-Spectrum Preclinical Antitumoral Activity

Janine Arts, Peter King, Ann Marin et al. · Clinical Cancer Research · 2009 · 232 citations

Medicine, Oncology, Pharmacology +12

Targeted delivery of RNA-cleaving DNA enzyme (DNAzyme) to tumor tissue by transferrin-modified, cyclodextrin-based particles

Suzie H. Pun, Frederik Tack, Nathalie C. Bellocq et al. · Cancer Biology & Therapy · 2004 · 200 citations · Full text

Pharmacy, Oncology, Pharmaceutics +17

R306465 is a novel potent inhibitor of class I histone deacetylases with broad-spectrum antitumoral activity against solid and haematological malignancies

Janine Arts, Patrick Angibaud, Ann Mariën et al. · British Journal of Cancer · 2007 · 89 citations · Full text

Medicine, Oncology, Pharmacology +15

Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activity

J Van heusden, R. Van Ginckel, Hélène Bruwiere et al. · British Journal of Cancer · 2002 · 86 citations · Full text

Medicine, Oncology, Pharmacology +13

Identification of a series of substituted 2-piperazinyl-5-pyrimidylhydroxamic acids as potent histone deacetylase inhibitors

Patrick Angibaud, Kristof Van Emelen, Laurence Decrane et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 18 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9