Josse A. Depla

AAV5-miHTT Lowers Huntingtin mRNA and Protein without Off-Target Effects in Patient-Derived Neuronal Cultures and Astrocytes

Sonay Keskin, Cynthia Brouwers, Marina Sogorb-González et al. · Molecular Therapy — Methods & Clinical Development · 2019 · 70 citations · Full text

Life Sciences, Molecular Biology, Neurobiology +17

Cerebral Organoids: A Human Model for AAV Capsid Selection and Therapeutic Transgene Efficacy in the Brain

Josse A. Depla, Marina Sogorb-González, Lance Mulder et al. · Molecular Therapy — Methods & Clinical Development · 2020 · 51 citations · Full text

Pharmacy, Biotechnology, Neuroscience +16

Enterovirus D68 Infection in Human Primary Airway and Brain Organoids: No Additional Role for Heparan Sulfate Binding for Neurotropism

Adithya Sridhar, Josse A. Depla, Lance Mulder et al. · Microbiology Spectrum · 2022 · 31 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Parechovirus infection in human brain organoids: host innate inflammatory response and not neuro-infectivity correlates to neurologic disease

Pamela E. Capendale, Inés García-Rodríguez, Anoop T. Ambikan et al. · Nature Communications · 2024 · 17 citations · Full text

Life Sciences, Infectious Diseases, Neuroscience +17