Amy Goodale

Defining a Cancer Dependency Map

Aviad Tsherniak, Francisca Vázquez, Phil Montgomery et al. · Cell · 2017 · 3.3K citations · Full text

Cancer Dependency Map, Medicine, Pathology +5

Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells

Robin M. Meyers, Jordan Bryan, James M. McFarland et al. · Nature Genetics · 2017 · 2.1K citations · Full text

Genetics, Genetic Engineering, Crispr–cas9 Essentiality Screens +7

Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities

Kendall R Sanson, Ruth E. Hanna, Mudra Hegde et al. · Nature Communications · 2018 · 1K citations · Full text

Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting

Andrew J. Aguirre, Robin M. Meyers, Barbara A. Weir et al. · Cancer Discovery · 2016 · 598 citations · Full text

Mutational processes shape the landscape of TP53 mutations in human cancer

Andrew O. Giacomelli, Xiaoping Yang, Robert Lintner et al. · Nature Genetics · 2018 · 566 citations · Full text

Genome Instability, Somatic Variant, Tumor Heterogeneity +10