Kai Prager

GGA proteins regulate retrograde transport of BACE1 from endosomes to the trans-Golgi network

Tina Wahle, Kai Prager, Nikolai Raffler et al. · Molecular and Cellular Neuroscience · 2005 · 131 citations

Life Sciences, Cell Biology, Molecular Biology +14

Inhibition of Glycosphingolipid Biosynthesis Reduces Secretion of the β-Amyloid Precursor Protein and Amyloid β-Peptide*[boxs]

Irfan Y. Tamboli, Kai Prager, Esther Barth et al. · Journal of Biological Chemistry · 2005 · 122 citations · Full text

Life Sciences, Neurobiology, Neuroscience +15

Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind, placebo-controlled phase 1a trial

Johannes Levin, Nand Sing, Sue Melbourne et al. · EBioMedicine · 2022 · 85 citations · Full text

Life Sciences, Pharmacokinetics, Pharmacology +17

Down-regulation of Endogenous Amyloid Precursor Protein Processing due to Cellular Aging

Andreas Kern, Birgit Roempp, Kai Prager et al. · Journal of Biological Chemistry · 2005 · 69 citations · Full text

Life Sciences, Biochemistry, Neuroscience +17

Loss of γ-Secretase Function Impairs Endocytosis of Lipoprotein Particles and Membrane Cholesterol Homeostasis

Irfan Y. Tamboli, Kai Prager, Dietmar Rudolf Thal et al. · Journal of Neuroscience · 2008 · 68 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17