Christine Lafleur

Disruption of histone methylation in developing sperm impairs offspring health transgenerationally

Keith Siklenka, Serap Erkek, Maren Godmann et al. · Science · 2015 · 523 citations

Spermatogenesis, Fertility, Epigenetic Change +22

Histone H3 lysine 4 trimethylation in sperm is transmitted to the embryo and associated with diet-induced phenotypes in the offspring

Ariane Lismer, Vanessa Dumeaux, Christine Lafleur et al. · Developmental Cell · 2021 · 125 citations · Full text

Biology, Chromatin, Histone H3 +14

Sperm histone H3 lysine 4 trimethylation is altered in a genetic mouse model of transgenerational epigenetic inheritance

Ariane Lismer, Keith Siklenka, Christine Lafleur et al. · Nucleic Acids Research · 2020 · 109 citations · Full text

Spermatogenesis, Epigenetic Change, Genetics +22

Sperm histone H3 lysine 4 tri-methylation serves as a metabolic sensor of paternal obesity and is associated with the inheritance of metabolic dysfunction

Anne-Sophie Pépin, Christine Lafleur, Romain Lambrot et al. · Molecular Metabolism · 2022 · 97 citations · Full text

Impaired Fertility and FSH Synthesis in Gonadotrope-Specific Foxl2 Knockout Mice

Stella Tran, Xiang Zhou, Christine Lafleur et al. · Molecular Endocrinology · 2013 · 73 citations · Full text

Spermatogenesis, Fertility, Genetics +23