Clint M. Upchurch

Macrophage phenotype and bioenergetics are controlled by oxidized phospholipids identified in lean and obese adipose tissue

Vlad Serbulea, Clint M. Upchurch, Michael S. Schappe et al. · Proceedings of the National Academy of Sciences · 2018 · 152 citations · Full text

Life Sciences, Biochemistry, Physiology +17

Macrophage acetyl-CoA carboxylase regulates acute inflammation through control of glucose and lipid metabolism

Scott Yeudall, Clint M. Upchurch, Philip V. Seegren et al. · Science Advances · 2022 · 84 citations · Full text

Life Sciences, Biochemistry, Immunology +17

Macrophages sensing oxidized DAMPs reprogram their metabolism to support redox homeostasis and inflammation through a TLR2-Syk-ceramide dependent mechanism

Vlad Serbulea, Clint M. Upchurch, Katelyn W. Ahern et al. · Molecular Metabolism · 2017 · 70 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Targeting oxidized phospholipids by AAV-based gene therapy in mice with established hepatic steatosis prevents progression to fibrosis

Clint M. Upchurch, Scott Yeudall, Caitlin Pavelec et al. · Science Advances · 2022 · 41 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2

Alex J.B. Kreutzberger, Volker Kiessling, Catherine A. Doyle et al. · eLife · 2020 · 40 citations · Full text

Life Sciences, Cell Biology, Endocrinology +17