M402, a Novel Heparan Sulfate Mimetic, Targets Multiple Pathways Implicated in Tumor Progression and Metastasis

He Zhou, Sucharita Roy, Edward Cochran, +19

PLoS ONE

ImmunologyTumor ProgressionPathologyImmunoeditingImmunotherapeutics +17

Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events

Olga Sobolev, Elisa Binda, Sean O’Farrell, +13

Nature Immunology

VaccinationVaccine TargetImmunologyAutoimmunityVaccine Efficacy +7

M281, an Anti‐FcRn Antibody: Pharmacodynamics, Pharmacokinetics, and Safety Across the Full Range of IgG Reduction in a First‐in‐Human Study

Leona Ling, Jan Hillson, Renger G. Tiessen, +9

Clinical Pharmacology & Therapeutics

Clinical ImmunologyImmunohematologyImmunodeficienciesImmunologyImmunodominance +22

Circulating Markers of Inflammation Persist in Children and Adults With Giant Aneurysms After Kawasaki Disease

Miroslaw Lech, Jamey Guess, Jay Duffner, +25

Circulation Genomic and Precision Medicine

Synthesis and Biological Evaluation of a Unique Heparin Mimetic Hexasaccharide for Structure–Activity Relationship Studies

Sucharita Roy, Ahmed El Hadri, S. Richard, +9

Journal of Medicinal Chemistry

GlycobiologyMolecular BiologyPolysaccharideChemical BiologyMedicinal Chemistry +14

Bioactivity screening of partially desulfated low-molecular-weight heparins: A structure/activity relationship study

Sucharita Roy, Hsuanchi Lai, Radouane Zouaoui, +7

Glycobiology

Regioselective Chemical ModificationsGlycobiologyImmunologyImmunotherapeuticsCancer Biology +18

Molecular profiling of rheumatoid arthritis patients reveals an association between innate and adaptive cell populations and response to anti-tumor necrosis factor

Victor Farutin, Thomas Prod’homme, Kevin W. McConnell, +21

Arthritis Research & Therapy

Nipocalimab, an immunoselective FcRn blocker that lowers IgG and has unique molecular properties

Nilufer P. Seth, Rui Xu, Matthew DuPrie, +26

mAbs

Characterization of heparin–protein interaction by saturation transfer difference (STD) NMR

Fei Yu, Sucharita Roy, Enrique Arevalo, +7

Analytical and Bioanalytical Chemistry

Protein ChemistrySaturation Transfer DifferenceBiochemistryNatural SciencesMolecular Biology +2

Characterization of Endogenous Human FcγRIII by Mass Spectrometry Reveals Site, Allele and Sequence Specific Glycosylation*

Nathaniel Washburn, Robin Meccariello, Jay Duffner, +10

Molecular & Cellular Proteomics