Ciara Metcalfe - Concepedia

Author

Ciara Metcalfe

Molecular Oncology (United States)ORCID

Also Known As

C Metcalfe, C. Metcalfe, C. R. Metcalfe, Ciara Metcalfe, Metcalfe, Ciara

204

Publications

2.8K

Citations

H-Index

Concepts

All Affiliations

Molecular Oncology (United States)MRC Laboratory of Molecular Biology WuXi AppTec (China)Ideaya Biosciences (United States)Charles River Laboratories (United Kingdom)

About

Ciara Metcalfe is an author at Molecular Oncology (United States) specializing in medicine, cell biology, and tumor biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	15	16	1.9K
2	Cell Biology	11	11	1.6K
3	Health Sciences	3	3	816
4	Natural Sciences	3	3	526
5	Biochemistry	1	1	182

Ciara Metcalfe

Publications

2.3K

Citations

H-Index

Page 1

	Year	Citations
Lgr5+ Stem Cells Are Indispensable for Radiation-Induced Intestinal Regeneration Ciara Metcalfe, Noelyn M. Kljavin, Ryan Ybarra, Cell stem cell Regenerative MedicineHealth SciencesMedicineAdult Stem CellStem Cell Research	2013	545
Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function Elaine E. Storm, Steffen Durinck, Felipe de Sousa e Melo, Nature Stem-cell FunctionCancer ResearchSignaling PathwayPtprk-rspo3 Colon TumoursMedicine	2015	248
Dynamic recruitment of axin by Dishevelled protein assemblies Thomas Schwarz, Ciara Metcalfe, Mariann Bienz Journal of Cell Science Wnt SignallingProtein AssemblyCytoskeletonCasein Kinase IepsilonCellular Physiology	2007	232
Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility Jane Guan, Wei Zhou, Marc Hafner, Cell Signal TransductionEndocrine MechanismMedicineHormonal ReceptorReceptor (Biochemistry)	2019	215
Inhibition of GSK3 by Wnt signalling – two contrasting models Ciara Metcalfe, Mariann Bienz Journal of Cell Science Wnt SignallingMolecular RegulationConserved Pppspxs MotifsCellular PhysiologyTranscriptional Regulation	2011	182
GDC-9545 (Giredestrant): A Potent and Orally Bioavailable Selective Estrogen Receptor Antagonist and Degrader with an Exceptional Preclinical Profile for ER+ Breast Cancer Jun Liang, Robert A. Blake, Jae H. Chang, Journal of Medicinal Chemistry	2021	130
The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer James D. Joseph, Beatrice Darimont, Wei Zhou, eLife Diverse ModelsBreast OncologyErα SignalingCancer Cell BiologyAnti-cancer Agent	2016	117
Stability elements in the LRP6 cytoplasmic tail confer efficient signalling upon DIX-dependent polymerization Ciara Metcalfe, Carolina Mendoza-Topaz, Juliusz Mieszczanek, Journal of Cell Science Molecular RegulationMolecular BiologyCytoskeletonSignaling PathwayDix-dependent Polymerization	2010	112
PTEN Loss Mitigates the Response of Medulloblastoma to Hedgehog Pathway Inhibition Ciara Metcalfe, Bruno Alicke, Ailey Crow, Cancer Research	2013	64
Modeling Targeted Inhibition of MEK and PI3 Kinase in Human Pancreatic Cancer Melissa R. Junttila, Vidusha Devasthali, Jason Chia‐Hsien Cheng, Molecular Cancer Therapeutics Systems BiologyOncologyPi3 KinasePi3k PathwaysPancreatic Cancer	2014	60

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