Graham R. Lawton

Development of a Manufacturing Route to Avibactam, a β-Lactamase Inhibitor

Matthew Ball, Alistair Boyd, Gareth J. Ensor et al. · Organic Process Research & Development · 2016 · 50 citations

Life Sciences, Biotechnology, Pharmaceutical Biotechnology +16

Analogues of 2-aminopyridine-based selective inhibitors of neuronal nitric oxide synthase with increased bioavailability

Graham R. Lawton, Hantamalala Ralay Ranaivo, Laura K. Chico et al. · Bioorganic & Medicinal Chemistry · 2009 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +6

Crystal Structures of Constitutive Nitric Oxide Synthases in Complex with De Novo Designed Inhibitors

Jotaro Igarashi, Huiying Li, J. Jamal et al. · Journal of Medicinal Chemistry · 2009 · 19 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Effect of potential amine prodrugs of selective neuronal nitric oxide synthase inhibitors on blood–brain barrier penetration

Richard B. Silverman, Graham R. Lawton, Hantamalala Ralay Ranaivo et al. · Bioorganic & Medicinal Chemistry · 2009 · 18 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Remote protection prevents unwanted cyclizations with 2-aminopyridines

Graham R. Lawton, Haitao Ji, Richard B. Silverman · Tetrahedron Letters · 2006 · 16 citations

Pharmacy, Medicinal Chemistry, Drug Discovery +3