Lekha Jain

Monosodium urate crystals alter the circadian clock in macrophages leading to loss of <scp>NLRP3</scp> inflammasome repression: Implications for timing of the gout flare

Dmitry Popov, Lekha Jain, Mariam Alhilali et al. · The FASEB Journal · 2023 · 23 citations · Full text

Life Sciences, Cell Biology, Immunology +17

IL-1β induces changes in expression of core circadian clock components PER2 and BMAL1 in primary human chondrocytes through the NMDA receptor/CREB and NF-κB signalling pathways

Mariam Alhilali, James I. Hearn, Lekha Jain et al. · Cellular Signalling · 2021 · 16 citations

Life Sciences, Neuroscience, Physiology +17

Phenotype and energy metabolism differ between osteoarthritic chondrocytes from male compared to female patients: Implications for sexual dimorphism in osteoarthritis development?

Lekha Jain, Caitlin A. Jardim, P Richard J Yulo et al. · Osteoarthritis and Cartilage · 2023 · 12 citations · Full text

Life Sciences, Orthopedic Surgery, Cellular Metabolism +12

TNF-α Differentially Regulates Cell Cycle Genes in Promyelocytic and Granulocytic HL-60/S4 Cells

Elsie Jacobson, Lekha Jain, Mark H. Vickers et al. · G3 Genes Genomes Genetics · 2019 · 11 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17