James I. Hearn

A novel EGR‐1 dependent mechanism for YB‐1 modulation of paclitaxel response in a triple negative breast cancer cell line

Annette Lasham, Sunali Mehta, Sandra Fitzgerald et al. · International Journal of Cancer · 2016 · 38 citations · Full text

Medicine, Oncology, Pharmacology +16

Altered N-methyl D-aspartate receptor subunit expression causes changes to the circadian clock and cell phenotype in osteoarthritic chondrocytes

Maggie L. Kalev‐Zylinska, James I. Hearn, Mark Zhu et al. · Osteoarthritis and Cartilage · 2018 · 24 citations · Full text

Life Sciences, Neuroscience, Physiology +17

Deletion of<i>Grin1</i>in mouse megakaryocytes reveals NMDA receptor role in platelet function and proplatelet formation

James I. Hearn, Taryn N. Green, Colin L. Hisey et al. · Blood · 2022 · 23 citations

Life Sciences, Cell Biology, Molecular Biology +11

Inhibition of NMDA receptor function with an anti-GluN1-S2 antibody impairs human platelet function and thrombosis

Taryn N. Green, Justin R. Hamilton, Marie‐Christine Morel‐Kopp et al. · Platelets · 2017 · 22 citations · Full text

Medicine, Neurology, Neuroscience +17

IL-1β induces changes in expression of core circadian clock components PER2 and BMAL1 in primary human chondrocytes through the NMDA receptor/CREB and NF-κB signalling pathways

Mariam Alhilali, James I. Hearn, Lekha Jain et al. · Cellular Signalling · 2021 · 16 citations

Life Sciences, Neuroscience, Physiology +17