Denise Westland

The malate-aspartate shuttle is important for de novo serine biosynthesis

Melissa H. Broeks, Nils W. F. Meijer, Denise Westland et al. · Cell Reports · 2023 · 62 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

MDH1 deficiency is a metabolic disorder of the malate–aspartate shuttle associated with early onset severe encephalopathy

Melissa H. Broeks, Hanan E. Shamseldin, Amal Alhashem et al. · Human Genetics · 2019 · 61 citations

Life Sciences, Neurobiology, Neuroscience +14

A YAP-centered mechanotransduction loop drives collective breast cancer cell invasion

Antoine Khalil, Daan Smits, Peter D. Haughton et al. · Nature Communications · 2024 · 44 citations · Full text

Life Sciences, Cell Biology, Oncology +16

Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells

Iris Glykofridis, Jaco C. Knol, Jesper A. Balk et al. · eLife · 2021 · 23 citations · Full text

Medicine, Genetics, Oncology +17

mTORC1 restricts TFE3 activity by auto-regulating its presence on lysosomes

Susan Zwakenberg, Denise Westland, Robert M. van Es et al. · Molecular Cell · 2024 · 19 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17