T-cell activation by transitory neo-antigens derived from distinct microbial pathways

Alexandra J. Corbett, Sidonia B. G. Eckle, Richard W. Birkinshaw, +15

Nature

Autoimmune DiseaseAdaptive Immune SystemT-regulatory CellImmunologyT-cell Activation +10

Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

Patricia T. Illing, J.P. Vivian, Nadine L. Dudek, +11

Nature

Autoimmune DiseaseImmunologyImmune Self-reactivitySelf-toleranceAutoimmunity +4

Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

Rangsima Reantragoon, Alexandra J. Corbett, Isaac G. Sakala, +17

The Journal of Experimental Medicine

Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers

Azad Rahimpour, Hui‐Fern Koay, Anselm Enders, +13

The Journal of Experimental Medicine

A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage

Hui‐Fern Koay, Nicholas A. Gherardin, Anselm Enders, +26

Nature Immunology

Developmental BiologyAutoimmune DiseaseLymphocyte DevelopmentAdaptive Immune SystemT-regulatory Cell +6

Human Leukocyte Antigen Class I-Restricted Activation of CD8+ T Cells Provides the Immunogenetic Basis of a Systemic Drug Hypersensitivity

Diana Chessman, Lyudmila Kostenko, Tessa Lethborg, +17

Immunity

InflammationImmunogenetic BasisAutoimmune DiseaseAllergyAdaptive Immune System +10

A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells

Sidonia B. G. Eckle, Richard W. Birkinshaw, Lyudmila Kostenko, +15

The Journal of Experimental Medicine

Recognition of vitamin B metabolites by mucosal-associated invariant T cells

Onisha Patel, Lars Kjer‐Nielsen, Jérôme Le Nours, +15

Nature Communications

MedicineBioanalysisImmunologyMetabolomic ProfilingAutoimmunity +7

Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals

Zhenjun Chen, Huimeng Wang, Criselle D’Souza, +14

Mucosal Immunology

InflammationMicrobial Riboflavin SynthesisMucosal ImmunologyMicrobial PathogensAdaptive Immune System +9

T Cell Allorecognition via Molecular Mimicry

W.A. Macdonald, Zhenjun Chen, Stéphanie Gras, +16

Immunity

Signal TransductionT-regulatory CellAntigen ProcessingSelf-toleranceMolecular Mimicry +4