Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

Patricia T. Illing, J.P. Vivian, Nadine L. Dudek, +11

Nature

Autoimmune DiseaseImmunologyImmune Self-reactivitySelf-toleranceAutoimmunity +4

A molecular basis for the association of the <i>HLA-DRB1</i> locus, citrullination, and rheumatoid arthritis

S.W. Scally, Jan Petersen, Soi Cheng Law, +14

The Journal of Experimental Medicine

Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients

Helen Benham, Hendrik J. Nel, Soi Cheng Law, +16

Science Translational Medicine

ImmunodeficienciesImmunologyImmune RegulationImmune SystemImmunotherapy +21

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP

Balasubramanian Krishnamurthy, Nadine L. Dudek, Mark McKenzie, +8

Journal of Clinical Investigation

Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells

Joshua D. Ooi, Jan Petersen, Yu H. Tan, +22

Nature

HlaAllergyAutoimmune DiseaseT-regulatory CellHla Immunogenetics +9

A Structural and Immunological Basis for the Role of Human Leukocyte Antigen DQ8 in Celiac Disease

Kate N. Henderson, Jason A. Tye–Din, Hugh H. Reid, +11

Immunity

Autoimmune DiseaseCeliac DiseaseImmunodeficienciesPathogenesisImmunology +9

Proinsulin-Specific, HLA-DQ8, and HLA-DQ8-Transdimer–Restricted CD4+ T Cells Infiltrate Islets in Type 1 Diabetes

Vimukthi Pathiraja, Janine P. Kuehlich, Peter D. Campbell, +14

Diabetes

Kinetics of Antigen Expression and Epitope Presentation during Virus Infection

Nathan P. Croft, Stewart A. Smith, Yik Chun Wong, +6

PLoS Pathogens

Epitope AbundanceImmunologyViral PathogenesisImmunodominanceEpitope Display +16

T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex

Dennis X. Beringer, Fleur S. Kleijwegt, Florian Wiede, +20

Nature Immunology

HistocompatibilityImmunogeneticsAutoimmune DiseaseHuman Leukocyte AntigenT-regulatory Cell +11

Revisiting the Arthritogenic Peptide Theory: Quantitative Not Qualitative Changes in the Peptide Repertoire of HLA–B27 Allotypes

Ralf B. Schittenhelm, Terry C.C. Lim Kam Sian, Pascal G. Wilmann, +2

Arthritis & Rheumatology