Concepedia

Margo Orlen

MO

4

Publications

234

Citations

4

H-Index

2018

Active since

Affiliations

University of Pennsylvania(Current)

Revolution Medicines (United States)

University of North Carolina at Chapel Hill

Columbia University Irving Medical Center

Brigham and Women's Hospital

Margo Orlen is an author at University of Pennsylvania specializing in neuropharmacology, cell biology, and signal transduction.

Top concepts

MedicineCell BiologyNeuroscienceCell SignalingNeuropharmacologySignal TransductionMolecular Physiology

Publications per year

2018–2025

4

Publications

4

Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer

Urszula N. Wasko, Jingjing Jiang, Tanner C. Dalton et al. · Nature · 2024 · 150 citations · Full text

The dopamine D2 receptor can directly recruit and activate GRK2 without G protein activation

Thomas F. Pack, Margo Orlen, Caroline Ray et al. · Journal of Biological Chemistry · 2018 · 51 citations · Full text

Signal Transduction, Molecular Physiology, G Protein-coupled Receptor +10

T-cell Dependency of Tumor Regressions and Complete Responses with RAS(ON) Multi-selective Inhibition in Preclinical Models of Pancreatic Ductal Adenocarcinoma

Margo Orlen, William P. Vostrejs, Rina Sor et al. · Cancer Discovery · 2025 · 23 citations · Full text

Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma

Urszula N. Wasko, Jingjing Jiang, Alvaro Curiel-Garcia et al. · 2023 · 10 citations · Full text

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