N. Marechal

Transition state mimics are valuable mechanistic probes for structural studies with the arginine methyltransferase CARM1

Matthijs J. van Haren, N. Marechal, N. Troffer-Charlier et al. · Proceedings of the National Academy of Sciences · 2017 · 41 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Structural basis of DNA crossover capture by <i>Escherichia coli</i> DNA gyrase

Marlène Vayssières, N. Marechal, Long Yun et al. · Science · 2024 · 37 citations · Full text

Life Sciences, Microbiology, Molecular Biology +11

Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors

Ludovic Halby, N. Marechal, Dany Pechalrieu et al. · Philosophical Transactions of the Royal Society B Biological Sciences · 2018 · 36 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +13

Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction–Reconstruction and Fragment-Growing Approach

Giulia Iannelli, Ciro Milite, N. Marechal et al. · Journal of Medicinal Chemistry · 2022 · 35 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +11

Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors

Vincent Cura, N. Marechal, N. Troffer-Charlier et al. · FEBS Journal · 2016 · 32 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16