Matthijs J. van Haren

Endotoxin-induced uveitis in the rat. The significance of intraocular interleukin-6.

Rick Hoekzema, Cora Verhagen, Matthijs J. van Haren et al. · PubMed · 1992 · 137 citations

Medicine, Immunology, Ophthalmology +17

Bisubstrate Inhibitors of Nicotinamide <i>N</i>-Methyltransferase (NNMT) with Enhanced Activity

Yongzhi Gao, Matthijs J. van Haren, Ed E. Moret et al. · Journal of Medicinal Chemistry · 2019 · 70 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Potent Inhibition of Nicotinamide <i>N</i>-Methyltransferase by Alkene-Linked Bisubstrate Mimics Bearing Electron Deficient Aromatics

Yongzhi Gao, Matthijs J. van Haren, Ned Buijs et al. · Journal of Medicinal Chemistry · 2021 · 65 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Macrocyclic peptides as allosteric inhibitors of nicotinamide <i>N</i> -methyltransferase (NNMT)

Matthijs J. van Haren, Yurui Zhang, Vito Thijssen et al. · RSC Chemical Biology · 2021 · 60 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide <i>N</i>-Methyltransferase

Matthijs J. van Haren, Javier Sastre Toraño, Davide Sartini et al. · Biochemistry · 2016 · 59 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13