Tsuyoshi Shuto

Activation of NF-κB by nontypeable <i>Hemophilus influenzae</i> is mediated by toll-like receptor 2-TAK1-dependent NIK–IKKα/β–IκBα and MKK3/6–p38 MAP kinase signaling pathways in epithelial cells

Tsuyoshi Shuto, Haidong Xu, Beinan Wang et al. · Proceedings of the National Academy of Sciences · 2001 · 257 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

Glucocorticoids Synergistically Enhance NontypeableHaemophilus influenzae-induced Toll-like Receptor 2 Expression via a Negative Cross-talk with p38 MAP Kinase

Tsuyoshi Shuto, Akira Imasato, Hirofumi Jono et al. · Journal of Biological Chemistry · 2002 · 152 citations · Full text

Life Sciences, Immunology, Microbiology +17

p53 Regulates Toll-Like Receptor 3 Expression and Function in Human Epithelial Cell Lines

Manabu Taura, Ayaka Eguma, Mary Ann Suico et al. · Molecular and Cellular Biology · 2008 · 127 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Promoter hypomethylation of Toll‐like receptor‐2 gene is associated with increased proinflammatory response towardbacterial peptidoglycan in cystic fibrosis bronchial epithelial cells

Tsuyoshi Shuto, Takashi Furuta, Mariko Oba et al. · The FASEB Journal · 2006 · 112 citations

Life Sciences, Immunology, Molecular Biology +17

Crystal structure of the IL-15–IL-15Rα complex, a cytokine-receptor unit presented in trans

Mami Chirifu, Chiharu Hayashi, Teruya Nakamura et al. · Nature Immunology · 2007 · 103 citations

Life Sciences, Immunology, Molecular Biology +13