Tsuyoshi Shuto

Activation of NF-κB by nontypeable <i>Hemophilus influenzae</i> is mediated by toll-like receptor 2-TAK1-dependent NIK–IKKα/β–IκBα and MKK3/6–p38 MAP kinase signaling pathways in epithelial cells

Tsuyoshi Shuto, Haidong Xu, Beinan Wang et al. · Proceedings of the National Academy of Sciences · 2001 · 257 citations · Full text

Glucocorticoids Synergistically Enhance NontypeableHaemophilus influenzae-induced Toll-like Receptor 2 Expression via a Negative Cross-talk with p38 MAP Kinase

Tsuyoshi Shuto, Akira Imasato, Hirofumi Jono et al. · Journal of Biological Chemistry · 2002 · 152 citations · Full text

P38 Map Kinase, Innate Immune System, Immunology +17

p53 Regulates Toll-Like Receptor 3 Expression and Function in Human Epithelial Cell Lines

Manabu Taura, Ayaka Eguma, Mary Ann Suico et al. · Molecular and Cellular Biology · 2008 · 127 citations · Full text

Microbial Pathogens, Innate Immune System, Immunology +20

Promoter hypomethylation of Toll‐like receptor‐2 gene is associated with increased proinflammatory response towardbacterial peptidoglycan in cystic fibrosis bronchial epithelial cells

Tsuyoshi Shuto, Takashi Furuta, Mariko Oba et al. · The FASEB Journal · 2006 · 112 citations

Inflammatory Lung Disease, Tlr2 Promoter, Lung Inflammation +18

The citrus flavonoids hesperetin and naringenin block the lipolytic actions of TNF-α in mouse adipocytes

Hiroki Yoshida, Norito Takamura, Tsuyoshi Shuto et al. · Biochemical and Biophysical Research Communications · 2010 · 99 citations

Inflammation, Biochemistry, Mouse Adipocytes +9