Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth

Jonathan B. Baell, David J. Leaver, S.J. Hermans, +49

Nature

Cancer ResearchChromatinTumour GrowthChromatin RemodelingMedicine +10

Activation of NF-κB by nontypeable <i>Hemophilus influenzae</i> is mediated by toll-like receptor 2-TAK1-dependent NIK–IKKα/β–IκBα and MKK3/6–p38 MAP kinase signaling pathways in epithelial cells

Tsuyoshi Shuto, Haidong Xu, Beinan Wang, +6

Proceedings of the National Academy of Sciences

Influenza viral neuraminidase primes bacterial coinfection through TGF-β–mediated expression of host cell receptors

Ning Li, Aihui Ren, Xiaoshuang Wang, +5

Proceedings of the National Academy of Sciences

Host ResponseMicrobial PathogensMedicinePathogenesisViral Pathogenesis +13

Novel Cytoplasmic Proteins of Nontypeable Haemophilus influenzae Up-regulate Human MUC5AC Mucin Transcription via a Positive p38 Mitogen-activated Protein Kinase Pathway and a Negative Phosphoinositide 3-Kinase-Akt Pathway

Beinan Wang, David Lim, Jiahuai Han, +3

Journal of Biological Chemistry

Induction of TGF-β1 and TGF-β1–dependent predominant Th17 differentiation by group A streptococcal infection

Beinan Wang, Thamotharampillai Dileepan, Sarah Briscoe, +4

Proceedings of the National Academy of Sciences

Integrin-linked kinase is an essential link between integrins and uptake of bacterial pathogens by epithelial cells

Beinan Wang, Ryan S. Yurecko, Shoukat Dedhar, +1

Cellular Microbiology

Integrin-linked KinaseMicrobial PathogensBacteriologyImmunologyBacterial Pathogens +15

Infection of Mycobacterium tuberculosis Promotes Both M1/M2 Polarization and MMP Production in Cigarette Smoke-Exposed Macrophages

Yanqing Le, Wenli Cao, Lu Zhou, +13

Frontiers in Immunology

cis Elements and trans factors are both important in strain-specific regulation of the leukotoxin gene in Actinobacillus actinomycetemcomitans

David Kolodrubetz, John K. Spitznagel, Beinan Wang, +3

Infection and Immunity

Periodontal DiseaseMedicineVirulence FactorPathogenesisBacteriology +11

Engagement of CD46 and α5β1 integrin by group A streptococci is required for efficient invasion of epithelial cells

Myrna S. Rezcallah, Kimberly Hodges, Darcy B. Gill, +3

Cellular Microbiology

Inflammatory Lung DiseaseMicrobial PathogensCell AdhesionImmunologyEfficient Invasion +14

Streptococcal modulation of cellular invasion via TGF-β1 signaling

Beinan Wang, Shaoying Li, Peter J. Southern, +1

Proceedings of the National Academy of Sciences

Microbial PathogensImmunologyBacterial PathogensMedical MicrobiologyInfection Control +17