Kyle D. Mansfield

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase

Mary Selak, Sean M. Armour, Elaine D. MacKenzie et al. · Cancer Cell · 2005 · 2.1K citations · Full text

Medicine, Cancer Biology, Oncology +14

Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

Robert D. Guzy, Beatrice Hoyos, Emmanuel Robin et al. · Cell Metabolism · 2005 · 1.5K citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

Acetylation of p53 Activates Transcription through Recruitment of Coactivators/Histone Acetyltransferases

Nickolai A. Barlev, Lin Liu, Nabil Chehab et al. · Molecular Cell · 2001 · 716 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-α activation

Kyle D. Mansfield, Robert D. Guzy, Yi Pan et al. · Cell Metabolism · 2005 · 608 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Multiple Factors Affecting Cellular Redox Status and Energy Metabolism Modulate Hypoxia-Inducible Factor Prolyl Hydroxylase Activity In Vivo and In Vitro

Yi Pan, Kyle D. Mansfield, Cara C. Bertozzi et al. · Molecular and Cellular Biology · 2006 · 322 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17