Sita Kugel Desmoulin

The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group

Amanda Larson Gedman, Qing Chen, Sita Kugel Desmoulin et al. · Leukemia · 2009 · 136 citations · Full text

Hematological Malignancy, Tumor Biology, Oncology Group +9

Synthesis and Biological Activity of a Novel Series of 6-Substituted Thieno[2,3-<i>d</i>]pyrimidine Antifolate Inhibitors of Purine Biosynthesis with Selectivity for High Affinity Folate Receptors over the Reduced Folate Carrier and Proton-Coupled Folate Transporter for Cellular Entry^†

Yijun Deng, Xilin Zhou, Sita Kugel Desmoulin et al. · Journal of Medicinal Chemistry · 2009 · 79 citations · Full text

Synthesis, Biological, and Antitumor Activity of a Highly Potent 6-Substituted Pyrrolo[2,3-<i>d</i>]pyrimidine Thienoyl Antifolate Inhibitor with Proton-Coupled Folate Transporter and Folate Receptor Selectivity over the Reduced Folate Carrier That Inhibits β-Glycinamide Ribonucleotide Formyltransferase

Lei Wang, Sita Kugel Desmoulin, Christina Cherian et al. · Journal of Medicinal Chemistry · 2011 · 68 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Pharmaceutical Chemistry +17

Synthesis and Antitumor Activity of a Novel Series of 6-Substituted Pyrrolo[2,3-<i>d</i>]pyrimidine Thienoyl Antifolate Inhibitors of Purine Biosynthesis with Selectivity for High Affinity Folate Receptors and the Proton-Coupled Folate Transporter over the Reduced Folate Carrier for Cellular Entry

Lei Wang, Christina Cherian, Sita Kugel Desmoulin et al. · Journal of Medicinal Chemistry · 2010 · 64 citations · Full text

Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter

Sita Kugel Desmoulin, Lei Wang, Eric C. Hales et al. · Molecular Pharmacology · 2011 · 60 citations · Full text