Sita Kugel Desmoulin

Author

Wayne State University

Also Known As

S Kugel Desmoulin, Sita Desmoulin, Sita Kugel Desmoulin

Publications

800

Citations

H-Index

Concepts

All Affiliations

Wayne State University The Barbara Ann Karmanos Cancer Institute Duquesne University Children's Hospital of Michigan Mayo Clinic

About

Sita Kugel Desmoulin is an author at Wayne State University specializing in medicine, pharmacology, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	5	5	329
2	Natural Sciences	3	3	147
3	Biochemistry	3	3	147
4	Cell Biology	2	2	195
5	Chemical Biology	2	2	79

Sita Kugel Desmoulin

Publications

650

Citations

H-Index

Page 1

	Year	Citations
The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group Amanda Larson Gedman, Qing Chen, Sita Kugel Desmoulin, Leukemia Hematological MalignancyTumor BiologyOncology GroupMixed-phenotype Acute LeukemiaImmunology	2009	136
Synthesis and Biological Activity of a Novel Series of 6-Substituted Thieno[2,3-<i>d</i>]pyrimidine Antifolate Inhibitors of Purine Biosynthesis with Selectivity for High Affinity Folate Receptors over the Reduced Folate Carrier and Proton-Coupled Folate Transporter for Cellular Entry<sup>†</sup> Yijun Deng, Xilin Zhou, Sita Kugel Desmoulin, Journal of Medicinal Chemistry	2009	79
Synthesis, Biological, and Antitumor Activity of a Highly Potent 6-Substituted Pyrrolo[2,3-<i>d</i>]pyrimidine Thienoyl Antifolate Inhibitor with Proton-Coupled Folate Transporter and Folate Receptor Selectivity over the Reduced Folate Carrier That Inhibits β-Glycinamide Ribonucleotide Formyltransferase Lei Wang, Sita Kugel Desmoulin, Christina Cherian, Journal of Medicinal Chemistry Pharmaceutical SciencePharmacotherapyPharmaceutical ChemistryMolecular PharmacologyMedicinal Chemistry	2011	68
Synthesis and Antitumor Activity of a Novel Series of 6-Substituted Pyrrolo[2,3-<i>d</i>]pyrimidine Thienoyl Antifolate Inhibitors of Purine Biosynthesis with Selectivity for High Affinity Folate Receptors and the Proton-Coupled Folate Transporter over the Reduced Folate Carrier for Cellular Entry Lei Wang, Christina Cherian, Sita Kugel Desmoulin, Journal of Medicinal Chemistry	2010	64
Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter Sita Kugel Desmoulin, Lei Wang, Eric C. Hales, Molecular Pharmacology	2011	60
Synergistic effects of multiple natural products in pancreatic cancer cells Zhiwei Wang, Sita Kugel Desmoulin, Sanjeev Banerjee, Life Sciences Multiple Natural ProductsTumor BiologyPancreatic CancerOncogenic AgentMedicine	2008	59
Targeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid Tumors Sita Kugel Desmoulin, Yiqiang Wang, Jianmei Wu, Molecular Pharmacology	2010	54
Synthesis and Biological Activity of 6-Substituted Pyrrolo[2,3-<i>d</i>]pyrimidine Thienoyl Regioisomers as Inhibitors of de Novo Purine Biosynthesis with Selectivity for Cellular Uptake by High Affinity Folate Receptors and the Proton-Coupled Folate Transporter over the Reduced Folate Carrier Lei Wang, Christina Cherian, Sita Kugel Desmoulin, Journal of Medicinal Chemistry Chemical BiologyPharmaceutical ChemistryTumor BiologyMolecular PharmacologyReduced Folate Carrier	2012	44
Identification and Functional Impact of Homo-oligomers of the Human Proton-coupled Folate Transporter Zhanjun Hou, Sita Kugel Desmoulin, Erika Etnyre, Journal of Biological Chemistry BiochemistryNatural SciencesMembrane TransportMolecular BiologyBiochemical Interaction	2011	35
Functional Loss of the Reduced Folate Carrier Enhances the Antitumor Activities of Novel Antifolates with Selective Uptake by the Proton-Coupled Folate Transporter Sita Kugel Desmoulin, Lei Wang, Lisa Polin, Molecular Pharmacology	2012	29

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