Antidiabetic activity of heart wood of Pterocarpus marsupium Roxb. and analysis of phytoconstituents.

Akansha Mishra, Swayam Prakash Srivastava, Sudeep Gautam, +3

PubMed

NutritionInsulin SignalingMetabolic SyndromeAntidiabetic ActivityHeart Wood +16

Identification of novel PTP1B inhibitors by pharmacophore based virtual screening, scaffold hopping and docking

Vishal M. Balaramnavar, Neha Rahuja, Swati Gupta, +13

European Journal of Medicinal Chemistry

Molecular DockingMedicinal ChemistryVirtual ScreeningScaffold HoppingHit Identification +10

A collagen domain–derived short adiponectin peptide activates APPL1 and AMPK signaling pathways and improves glucose and fatty acid metabolisms

Mohd Sayeed, Sudeep Gautam, Devesh Pratap Verma, +4

Journal of Biological Chemistry

Aegeline from Aegle marmelos stimulates glucose transport via Akt and Rac1 signaling, and contributes to a cytoskeletal rearrangement through PI3K/Rac1

Sudeep Gautam, Nayab Ishrat, Rohit Singh, +1

European Journal of Pharmacology

Aegle Marmelos StimulatesSignal TransductionCytoskeletonRac1 SignalingCytoskeletal Rearrangement +8

The signaling pathways implicated in impairment of hepatic autophagy in glycogen storage disease type Ia

Sudeep Gautam, Lisa Zhang, Irina Arnaoutova, +2

Human Molecular Genetics

MitophagySignaling PathwaysMetabolic SyndromeCell AutophagySignaling Pathway +26

4-Hydroxyisoleucine improves insulin resistance by promoting mitochondrial biogenesis and act through AMPK and Akt dependent pathway

Arun Rawat, Venkateswarlu Korthikunta, Sudeep Gautam, +3

Fitoterapia

Metabolic SyndromeAkt Dependent PathwayMitochondrial BiogenesisMitochondrial FunctionBiochemistry +11

Bioactivity-guided chemical analysis of Melia azedarach L. (Meliaceae), displaying antidiabetic activity

Mohammad Faheem Khan, Arun Rawat, B. T. Pawar, +3

Fitoterapia

Medicinal ChemistryBiochemistryMedicineNatural SciencesMelia Azedarach L. +9

Ethanolic Extract of Allium cepa Stimulates Glucose Transporter Typ 4-Mediated Glucose Uptake by the Activation of Insulin Signaling

Sudeep Gautam, Savita Pal, Rakesh Maurya

Planta Medica

Hepatocyte cannabinoid 1 receptor nullification alleviates toxin-induced liver damage via NF-κB signaling

Yoo Kim, Sudeep Gautam, Kanikkai Raja Aseer, +10

Cell Death and Disease

4-Hydroxyisoleucine attenuates the inflammation-mediated insulin resistance by the activation of AMPK and suppression of SOCS-3 coimmunoprecipitation with both the IR-β subunit as well as IRS-1

Sudeep Gautam, Nayab Ishrat, Pragya D. Yadav, +3

Molecular and Cellular Biochemistry

Immune RegulationImmunologySocs-3 CoimmunoprecipitationInsulin SignalingInflammation +14