Estella A. Newcombe

Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles

Sven Hennig, Geraldine Kong, Taro Mannen et al. · The Journal of Cell Biology · 2015 · 338 citations · Full text

Protein Assembly, Subnuclear Paraspeckles, Molecular Biology +22

Huntingtin Inclusions Trigger Cellular Quiescence, Deactivate Apoptosis, and Lead to Delayed Necrosis

Yasmin M. Ramdzan, Mikhail M. Trubetskov, Angelique R. Ormsby et al. · Cell Reports · 2017 · 127 citations · Full text

How phosphorylation impacts intrinsically disordered proteins and their function

Estella A. Newcombe, Elise Delaforge, Rasmus Hartmann‐Petersen et al. · Essays in Biochemistry · 2022 · 92 citations · Full text

Protein Assembly, Molecular Biology, Many Idps +16

Refinement of α-Synuclein Ensembles Against SAXS Data: Comparison of Force Fields and Methods

Mustapha Carab Ahmed, Line K. Skaanning, Alexander Jussupow et al. · Frontiers in Molecular Biosciences · 2021 · 90 citations · Full text

Engineering, Molecular Biology, Force Fields +22

Tadpole-like Conformations of Huntingtin Exon 1 Are Characterized by Conformational Heterogeneity that Persists regardless of Polyglutamine Length

Estella A. Newcombe, Kiersten M. Ruff, Ashish Sethi et al. · Journal of Molecular Biology · 2018 · 75 citations · Full text

Protein Assembly, Molecular Biology, Conformational Heterogeneity +16