Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide

Jesper Lau, Paw Bloch, Lauge Schäffer, +14

Journal of Medicinal Chemistry

Albumin AffinityGlycobiologyPeptide SciencePeptide TherapeuticsPharmacotherapy +17

Traveling‐wave ion mobility mass spectrometry of protein complexes: accurate calibrated collision cross‐sections of human insulin oligomers

Rune Salbo, Matthew F. Bush, Helle Naver, +5

Rapid Communications in Mass Spectrometry

A comparison of conformational energies calculated by several molecular mechanics methods

Klaus Gundertofte, Tommy Liljefors, Per‐Ola Norrby, +1

Journal of Computational Chemistry

EngineeringMolecular BiologyComputational ChemistryChemistryForce Fields +16

Novel Tricyclic-α-alkyloxyphenylpropionic Acids:  Dual PPARα/γ Agonists with Hypolipidemic and Antidiabetic Activity

Per Sauerberg, Ingrid Pettersson, Lone Jeppesen, +17

Journal of Medicinal Chemistry

Synthesis and Biological and Structural Characterization of the Dual-Acting Peroxisome Proliferator-Activated Receptor α/γ Agonist Ragaglitazar

Søren Ebdrup, Ingrid Pettersson, Hanne B. Rasmussen, +7

Journal of Medicinal Chemistry

Medicinal ChemistryStructural CharacterizationHppargamma ReceptorBiochemistryFunctional Selectivity +10

Insulin analog with additional disulfide bond has increased stability and preserved activity

Tine N. Vinther, Mathias Norrman, Ulla Ribel, +9

Protein Science

Molecular PharmacologyBiochemistryG Protein-coupled ReceptorMedicineInsulin Management +8

Small molecule ago-allosteric modulators of the human glucagon-like peptide-1 (hGLP-1) receptor

Min Teng, Michael D. Johnson, Christine K. Thomas, +19

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyMolecular PhysiologySignal TransductionBiochemistryG Protein-coupled Receptor +11

Benzene‐benzene (phenyl‐phenyl) interactions in MM2/MMP2 molecular mechanics calculations

Ingrid Pettersson, Tommy Liljefors

Journal of Computational Chemistry

EngineeringNatural SciencesBenzene‐benzene InteractionsBenzene Dimer PotentialsComputational Chemistry +7

A comparison of conformational energies calculated by molecular mechanics (MM2(85), Sybyl 5.1, Sybyl 5.21, and ChemX) and semiempirical (AM1 and PM3) methods

Klaus Gundertofte, Jonas Palm, Ingrid Pettersson, +1

Journal of Computational Chemistry

EngineeringComputational ChemistryChemistryForce FieldsMolecular Dynamics +14

New leads of metallo-β-lactamase inhibitors from structure-based pharmacophore design

Lars Olsen, Sandra Jost, Hans‐Werner Adolph, +3

Bioorganic & Medicinal Chemistry

Molecular PharmacologyMedicinal ChemistryMedicineRational Drug DesignNew Leads +5