Sherona Sirkisoon

Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer

Sherona Sirkisoon, Richard L. Carpenter, Tadas Rimkus et al. · Oncogene · 2018 · 94 citations · Full text

Breast Oncology, Triple-negative Breast Cancers, Medicine +7

TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment

Sherona Sirkisoon, Richard L. Carpenter, Tadas Rimkus et al. · Oncogene · 2019 · 83 citations

Lineage Plasticity, Medicine, Stem Cells +11

Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis

Daniel Doheny, Sherona Sirkisoon, Richard L. Carpenter et al. · Oncogene · 2020 · 79 citations · Full text

Breast Oncology, Signaling Pathway, Medicine +12

Breast cancer extracellular vesicles-derived miR-1290 activates astrocytes in the brain metastatic microenvironment via the FOXA2→CNTF axis to promote progression of brain metastases

Sherona Sirkisoon, Grace L. Wong, Noah R. Aguayo et al. · Cancer Letters · 2022 · 57 citations · Full text

Foxa2→cntf Axis, Brain Metastases, Medicine +7

The gain-of-function GLI1 transcription factor TGLI1 enhances expression of VEGF-C and TEM7 to promote glioblastoma angiogenesis

Richard L. Carpenter, Ivy Paw, Hu Zhu et al. · Oncotarget · 2015 · 53 citations · Full text