Eric J. Lachacz

Exquisitely Specific Bisubstrate Inhibitors of c-Src Kinase

Kristoffer Brandvold, Shana Marie Santos, Meghan E. Breen et al. · ACS Chemical Biology · 2015 · 27 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +14

UM-164: A Potent c-Src/p38 Kinase Inhibitor with <i>In Vivo</i> Activity against Triple-Negative Breast Cancer

Rabia A. Gilani, Sameer Phadke, Li Bao et al. · Clinical Cancer Research · 2016 · 27 citations

Medicine, Oncology, Pharmacology +17

Substrate Activity Screening with Kinases: Discovery of Small‐Molecule Substrate‐Competitive c‐Src Inhibitors

Meghan E. Breen, Michael E. Steffey, Eric J. Lachacz et al. · Angewandte Chemie International Edition · 2014 · 22 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +13

Selective Proteolysis to Study the Global Conformation and Regulatory Mechanisms of c-Src Kinase

Michael P. Agius, Kristin S. Ko, Taylor K. Johnson et al. · ACS Chemical Biology · 2019 · 17 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Molecular determinants of drug response in TNBC cell lines

Nathan Merrill, Eric J. Lachacz, Nathalie M. Vandecan et al. · Breast Cancer Research and Treatment · 2019 · 15 citations · Full text

Medicine, Cancer Biology, Molecular Biology +14