Marc Usart

Single-cell lineage tracing unveils a role for TCF15 in haematopoiesis

Alejo Rodriguez-Fraticelli, Caleb Weinreb, Shou‐Wen Wang et al. · Nature · 2020 · 283 citations · Full text

Cell Lineage, Single Cell Sequencing, Medicine +7

IL-1β promotes MPN disease initiation by favoring early clonal expansion of <i>JAK2</i>-mutant hematopoietic stem cells

Shivam Rai, Yang Zhang, Élodie Grockowiak et al. · Blood Advances · 2024 · 23 citations · Full text

The glutaminase inhibitor CB-839 targets metabolic dependencies of <i>JAK2</i>-mutant hematopoiesis in MPN

Marc Usart, Nils Hansen, Jan Stetka et al. · Blood Advances · 2024 · 16 citations · Full text

Loss of <i>Dnmt3a</i> increases self-renewal and resistance to pegIFN-α in <i>JAK2</i>-V617F–positive myeloproliferative neoplasms

Marc Usart, Jan Stetka, Damien Luque Paz et al. · Blood · 2024 · 16 citations · Full text

The Second Generation Type II JAK2 Inhibitor, AJ1-10502, Demonstrates Enhanced Selectivity, Improved Therapeutic Efficacy and Reduced Mutant Cell Fraction Compared to Type I JAK2 Inhibitors in Models of Myeloproliferative Neoplasms (MPNs)

Shivam Rai, Jan Stetka, Marc Usart et al. · Blood · 2022 · 12 citations