Viviane Brel

F14512, a Potent Antitumor Agent Targeting Topoisomerase II Vectored into Cancer Cells via the Polyamine Transport System

Jean‐Marc Barret, Anna Kruczynski, Stéphane Vispé et al. · Cancer Research · 2008 · 95 citations · Full text

Medicine, Oncology, Pharmacology +14

Synthesis of conjugated spermine derivatives with 7-nitrobenzoxadiazole (NBD), rhodamine and bodipy as new fluorescent probes for the polyamine transport system

Yves Guminski, Martial Grousseaud, Sandrine Cugnasse et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 45 citations

Natural Sciences, Chemical Biology, Molecular Biology +9

Cytotoxicity and cell death mechanisms induced by the polyamine-vectorized anti-cancer drug F14512 targeting topoisomerase II

Viviane Brel, Jean‐Philippe Annereau, Stéphane Vispé et al. · Biochemical Pharmacology · 2011 · 39 citations

Medicine, Oncology, Pharmacology +16

A fluorescent biomarker of the polyamine transport system to select patients with AML for F14512 treatment

Jean‐Philippe Annereau, Viviane Brel, Charles Dumontet et al. · Leukemia Research · 2010 · 35 citations

Medicine, Molecular Medicine, Pharmacology +10

F14512, a polyamine-vectorized anti-cancer drug, currently in clinical trials exhibits a marked preclinical anti-leukemic activity

Anna Kruczynski, Arnaud Pillon, Laurent Créancier et al. · Leukemia · 2013 · 35 citations

Medicine, Oncology, Pharmacology +8