Patients With Antithyroid Antibodies Are Prone To Develop Destructive Thyroiditis by Nivolumab: A Prospective Study

Tomoko Kobayashi, Shintaro Iwama, Yoshinori Yasuda, +20

Journal of the Endocrine Society

PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice

Ryoichi Banno, Derek J. Zimmer, Bart C. De Jonghe, +4

Journal of Clinical Investigation

Flash glucose monitoring helps achieve better glycemic control than conventional self-monitoring of blood glucose in non-insulin-treated type 2 diabetes: a randomized controlled trial

Eri Wada, Takeshi Onoue, Tomoko Kobayashi, +18

BMJ Open Diabetes Research & Care

Pituitary dysfunction induced by immune checkpoint inhibitors is associated with better overall survival in both malignant melanoma and non-small cell lung carcinoma: a prospective study

Tomoko Kobayashi, Shintaro Iwama, Yoshinori Yasuda, +23

Journal for ImmunoTherapy of Cancer

Glucocorticoids Increase Neuropeptide Y and Agouti-Related Peptide Gene Expression via Adenosine Monophosphate-Activated Protein Kinase Signaling in the Arcuate Nucleus of Rats

Hiroshi Shimizu, Hiroshi Arima, Minemori Watanabe, +6

Endocrinology

NeuropeptidesSignal TransductionArcuate NucleusPhysiologyAmpk Signaling +13

Hypothalamic Contribution to Pituitary Functions Is Recapitulated In Vitro Using 3D-Cultured Human iPS Cells

Takatoshi Kasai, Hidetaka Suga, Mayu Sakakibara, +19

Cell Reports

Independent Pituitary InductionHypothalamic CircuitsEmbryologyPituitary GlandNeuroendocrine Mechanism +20

CD4 ⁺ T cells are essential for the development of destructive thyroiditis induced by anti–PD-1 antibody in thyroglobulin-immunized mice

Yoshinori Yasuda, Shintaro Iwama, Daisuke Sugiyama, +19

Science Translational Medicine

Anti-thyroid antibodies and thyroid echo pattern at baseline as risk factors for thyroid dysfunction induced by anti-programmed cell death-1 antibodies: a prospective study

Norio Okada, Shintaro Iwama, Takayuki Okuji, +29

British Journal of Cancer

Anti-pituitary antibodies and susceptible human leukocyte antigen alleles as predictive biomarkers for pituitary dysfunction induced by immune checkpoint inhibitors

Tomoko Kobayashi, Shintaro Iwama, Daisuke Sugiyama, +13

Journal for ImmunoTherapy of Cancer

Deficiency of PTP1B Attenuates Hypothalamic Inflammation via Activation of the JAK2-STAT3 Pathway in Microglia

Taku Tsunekawa, Ryoichi Banno, Akira Mizoguchi, +10

EBioMedicine