Richard B. Westkaemper

Structure of the human κ-opioid receptor in complex with JDTic

Huixian Wu, Daniel Wacker, Mauro Mileni et al. · Nature · 2012 · 871 citations · Full text

Medicine, Molecular Biology, Pharmacology +12

Salvinorin A: A potent naturally occurring nonnitrogenous κ opioid selective agonist

Bryan L. Roth, Karen Baner, Richard B. Westkaemper et al. · Proceedings of the National Academy of Sciences · 2002 · 780 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Identification of the Molecular Mechanisms by Which the Diterpenoid Salvinorin A Binds to κ-Opioid Receptors

Feng Yan, Philip D. Mosier, Richard B. Westkaemper et al. · Biochemistry · 2005 · 91 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Differential ergoline and ergopeptine binding to 5-hydroxytryptamine2A receptors: ergolines require an aromatic residue at position 340 for high affinity binding.

M S Choudhary, Nancy A. Sachs, Ahmet Uluer et al. · Molecular Pharmacology · 1995 · 91 citations

Medicine, Molecular Biology, Pharmacology +14

Design, Synthesis, and Biological Evaluation of 6α- and 6β-<i>N</i>-Heterocyclic Substituted Naltrexamine Derivatives as μ Opioid Receptor Selective Antagonists

Li Guo, Lindsey C. Aschenbach, Jianyang Chen et al. · Journal of Medicinal Chemistry · 2009 · 88 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17