M S Choudhary

Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.

Bryan L. Roth, S Craigo, M S Choudhary et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 211 citations

Medicine, Pharmacology, Psychiatry +12

Identification of Conserved Aromatic Residues Essential for Agonist Binding and Second Messenger Production at 5-Hydroxytryptamine2A Receptors

Bryan L. Roth, Menachem Shoham, M S Choudhary et al. · Molecular Pharmacology · 1997 · 134 citations

Medicine, Pharmacology, Molecular Pharmacology +16

A single point mutation (Phe340-->Leu340) of a conserved phenylalanine abolishes 4-[125I]iodo-(2,5-dimethoxy)phenylisopropylamine and [3H]mesulergine but not [3H]ketanserin binding to 5-hydroxytryptamine2 receptors.

M S Choudhary, S Craigo, Bryan L. Roth · PubMed · 1993 · 118 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Differential ergoline and ergopeptine binding to 5-hydroxytryptamine2A receptors: ergolines require an aromatic residue at position 340 for high affinity binding.

M S Choudhary, Nancy A. Sachs, Ahmet Uluer et al. · Molecular Pharmacology · 1995 · 91 citations

Medicine, Molecular Biology, Pharmacology +14

5-Hydroxytryptamine2A (5-HT2A) receptor desensitization can occur without down-regulation.

Bryan L. Roth, Esa-Pekka Pälvimäki, Susan A. Berry et al. · Journal of Pharmacology and Experimental Therapeutics · 1995 · 90 citations

Medicine, Neurobiology, Pharmacology +16