Peter Orth

Crystal structure of photosystem II from Synechococcus elongatus at 3.8 Å resolution

Athina Zouni, H. T. Witt, Jan Kern et al. · Nature · 2001 · 1.9K citations

Photosystem Ii, Crystal Structure, Photosystems +10

Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system.

Wolfram Saenger, Winfried Hinrichs, Peter Orth et al. · Nature Structural Biology · 2000 · 468 citations

Transcriptional Regulation, Systems Biology, Molecular Regulation +8

The Mechanism of Atrial Antiarrhythmic Action of RSD1235

David Fedida, Peter Orth, JANET Y.C. CHEN et al. · Journal of Cardiovascular Electrophysiology · 2005 · 194 citations

Discovery of the 3-Imino-1,2,4-thiadiazinane 1,1-Dioxide Derivative Verubecestat (MK-8931)–A β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor for the Treatment of Alzheimer’s Disease

Jack D. Scott, Sarah W. Li, Andrew P. J. Brunskill et al. · Journal of Medicinal Chemistry · 2016 · 161 citations · Full text

Neurochemical Biomarkers, Peptide Science, Enzyme 1 +19

A Series of Novel, Highly Potent, and Orally Bioavailable Next-Generation Tricyclic Peptide PCSK9 Inhibitors

Thomas J. Tucker, Mark W. Embrey, Candice Alleyne et al. · Journal of Medicinal Chemistry · 2021 · 140 citations · Full text