Concepedia

Peter Orth

PO

Statistics

Publications

54

Citations

5.7K

H-Index

36

Active since

1987

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

Freie Universität Berlin

United States Military Academy

Friedrich-Alexander-Universität Erlangen-Nürnberg

Cardiome (Canada)

Peter Orth is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in medicinal chemistry, drug discovery, and pharmacology.

Publications per year

1987–2025

54

Publications

54

Crystal structure of photosystem II from Synechococcus elongatus at 3.8 Å resolution

Athina Zouni, H. T. Witt, Jan Kern et al. · Nature · 2001 · 1.9K citations

Life Sciences, Biochemistry, Biophysics +14

Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system.

Wolfram Saenger, Winfried Hinrichs, Peter Orth et al. · Nature Structural Biology · 2000 · 473 citations

Life Sciences, Genetics, Molecular Biology +16

The Mechanism of Atrial Antiarrhythmic Action of RSD1235

David Fedida, Peter Orth, JANET Y.C. CHEN et al. · Journal of Cardiovascular Electrophysiology · 2005 · 194 citations

Medicine, Cardiology, Pharmacology +17

Discovery of the 3-Imino-1,2,4-thiadiazinane 1,1-Dioxide Derivative Verubecestat (MK-8931)–A β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor for the Treatment of Alzheimer’s Disease

Jack D. Scott, Sarah W. Li, Andrew P. J. Brunskill et al. · Journal of Medicinal Chemistry · 2016 · 165 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

A Series of Novel, Highly Potent, and Orally Bioavailable Next-Generation Tricyclic Peptide PCSK9 Inhibitors

Thomas J. Tucker, Mark W. Embrey, Candice Alleyne et al. · Journal of Medicinal Chemistry · 2021 · 152 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

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