Jiahai Zhou

The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response

Jiahai Zhou, Chuan Yin Liu, Sung Hoon Back et al. · Proceedings of the National Academy of Sciences · 2006 · 365 citations · Full text

Crystal Structure, Conserved Dimerization Interface, Molecular Biology +21

Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action

Yan Yan, Qikun Liu, Xin Zang et al. · Nature · 2018 · 256 citations · Full text

Mode Of Action, Biosynthesis, Engineering +12

Stereodivergent Protein Engineering of a Lipase To Access All Possible Stereoisomers of Chiral Esters with Two Stereocenters

Jian Xu, Yixin Cen, Warispreet Singh et al. · Journal of the American Chemical Society · 2019 · 188 citations · Full text

Crystal Structure, Bioorganic Chemistry, Engineering +19

Catalytic Asymmetric Reduction of Difficult-to-Reduce Ketones: Triple-Code Saturation Mutagenesis of an Alcohol Dehydrogenase

Zhoutong Sun, Richard Lonsdale, Adriana Ilie et al. · ACS Catalysis · 2016 · 138 citations

Engineering, Organic Chemistry, Chemistry +17

Structure-Guided Triple-Code Saturation Mutagenesis: Efficient Tuning of the Stereoselectivity of an Epoxide Hydrolase

Zhoutong Sun, Richard Lonsdale, Lian Wu et al. · ACS Catalysis · 2016 · 135 citations

Bioorganic Chemistry, Triple Code, Engineering +20