Yixin Cen

Stereodivergent Protein Engineering of a Lipase To Access All Possible Stereoisomers of Chiral Esters with Two Stereocenters

Jian Xu, Yixin Cen, Warispreet Singh et al. · Journal of the American Chemical Society · 2019 · 188 citations · Full text

Crystal Structure, Bioorganic Chemistry, Engineering +19

Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution

Yixin Cen, Warispreet Singh, M Arkin et al. · Nature Communications · 2019 · 97 citations · Full text

Structural Insight into the Catalytic Mechanism of the Endoperoxide Synthase FtmOx1

Lian Wu, Zhanfeng Wang, Yixin Cen et al. · Angewandte Chemie International Edition · 2021 · 37 citations

Biosynthesis, Biochemistry, Natural Sciences +15

Stereoselectivity-Tailored, Metal-Free Hydrolytic Dynamic Kinetic Resolution of Morita–Baylis–Hillman Acetates Using an Engineered Lipase–Organic Base Cocatalyst

Bo Xia, Jian Xu, Zhiwei Xiang et al. · ACS Catalysis · 2017 · 32 citations

Engineering, Chiral Mbh Alcohols, Morita–baylis–hillman Acetates +17

Highly Focused Library‐Based Engineering of <i>Candida antarctica</i> Lipase B with (<i>S</i>)‐Selectivity Towards <i>sec</i>‐Alcohols

Yixin Cen, Danyang Li, Jian Xu et al. · Advanced Synthesis & Catalysis · 2018 · 25 citations

Lipid Analysis, Engineering, Calb Variant +17