Oligodendrocyte dysfunction in the pathogenesis of amyotrophic lateral sclerosis

Thomas Philips, André Bento‐Abreu, Annelies Nonneman, +9

Brain

Ventral Grey MatterNeurodegenerative DiseasesAmyotrophic Lateral SclerosisNeurological DisorderMedicine +9

ELP3 Controls Active Zone Morphology by Acetylating the ELKS Family Member Bruchpilot

Katarzyna Miśkiewicz, Liya Jose, André Bento‐Abreu, +8

Neuron

BiologyPattern FormationDevelopmental BiologyMorphogenesisMedicine

Rapamycin increases survival in ALS mice lacking mature lymphocytes

Kim A. Staats, Sara Hernández, Susann Schönefeldt, +6

Molecular Neurodegeneration

Peroxisome proliferator‐activated receptor‐alpha is required for the neurotrophic effect of oleic acid in neurons

André Bento‐Abreu, Arantxa Tabernero, José M. Medina

Journal of Neurochemistry

Megalin is a receptor for albumin in astrocytes and is required for the synthesis of the neurotrophic factor oleic acid

André Bento‐Abreu, Ana Luisa Velasco, Erica Polo‐Hernández, +3

Journal of Neurochemistry

Cellular PhysiologyNeuroinflammationOleic AcidEpendymaAutophagy +15

Albumin endocytosis via megalin in astrocytes is caveola‐ and Dab‐1 dependent and is required for the synthesis of the neurotrophic factor oleic acid

André Bento‐Abreu, Ana Luisa Velasco, Erica Polo‐Hernández, +4

Journal of Neurochemistry

Cellular PhysiologyAlbumin EndocytosisCaveolae InternalizationEndocytic PathwayNeurochemistry +14

Genetic ablation of IP₃receptor 2 increases cytokines and decreases survival of<i>SOD1^G93A</i>mice

Kim A. Staats, Stéphanie Humblet‐Baron, André Bento‐Abreu, +12

Human Molecular Genetics

Genetic ablation of phospholipase C delta 1 increases survival in SOD1G93A mice

Kim A. Staats, Lawrence Van Helleputte, Ashley Jones, +14

Neurobiology of Disease

Knockout MouseSignal TransductionSignaling PathwayNatural SciencesGenetics +12

AAV9-mediated gene delivery of MCT1 to oligodendrocytes does not provide a therapeutic benefit in a mouse model of ALS

Caroline Eykens, Elisabeth Rossaert, Sandra Duqué, +13

Molecular Therapy — Methods & Clinical Development

Neurodegenerative DiseasesNeuroregenerationAav9-mediated Gene DeliveryTherapeutic BenefitAmyotrophic Lateral Sclerosis +9

Health Impact and Cost-Effectiveness of Implementing Gender-Neutral Vaccination With the 9-Valent Human Papillomavirus Vaccine in Belgium

Steven Simoens, André Bento‐Abreu, Barbara Merckx, +5

Frontiers in Pharmacology