Masayoshi Sakaguchi

Role of Altered Renal Lipid Metabolism in the Development of Renal Injury Induced by a High-Fat Diet

Shinji Kume, Takashi Uzu, Shin‐ichi Araki et al. · Journal of the American Society of Nephrology · 2007 · 279 citations · Full text

Nutrition, Metabolic Disorder, High-fat Diet +19

Structural and functional changes in the kidneys of high-fat diet-induced obese mice

Naoko Deji, Shinji Kume, Shin‐ichi Araki et al. · American Journal of Physiology-Renal Physiology · 2008 · 260 citations

Nutrition, Metabolic Disorder, Renal Pathology +22

Fenofibrate, a PPARα agonist, has renoprotective effects in mice by enhancing renal lipolysis

Yuki Tanaka, Shinji Kume, Shin‐ichi Araki et al. · Kidney International · 2011 · 181 citations · Full text

Molecular Pharmacology, Molecular Physiology, Medicine +11

Inhibition of mTOR signaling with rapamycin attenuates renal hypertrophy in the early diabetic mice

Masayoshi Sakaguchi, Motohide Isono, Keiji Isshiki et al. · Biochemical and Biophysical Research Communications · 2005 · 163 citations

Metabolic Syndrome, Insulin Signaling, Urology +14

Exendin-4 has an anti-hypertensive effect in salt-sensitive mice model

Kunio Hirata, Shinji Kume, Shin‐ichi Araki et al. · Biochemical and Biophysical Research Communications · 2009 · 159 citations

Inflammation, Hypertension, Molecular Physiology +7