Low-dose metformin targets the lysosomal AMPK pathway through PEN2

Teng Ma, Xiao Tian, Baoding Zhang, +32

Nature

The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK

Chen‐Song Zhang, Mengqi Li, Yu Wang, +42

Nature Metabolism

Aldo-keto ReductaseMetabolic RemodelingInsulin SignalingMetabolic SyndromeAldolase Inhibitor +17

Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing

Qi Qu, Yan Chen, Yu Wang, +32

Nature

Lithocholic acid phenocopies anti-ageing effects of calorie restriction

Qi Qu, Yan Chen, Yu Wang, +24

Nature

Heterogeneous gold catalysts for selective hydrogenation: from nanoparticles to atomically precise nanoclusters

Jianbo Zhao, Liming Ge, Haifeng Yuan, +5

Nanoscale

AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine

Mengqi Li, Yu Wang, Xiaoyan Wei, +30

Cell Research

A new ALK inhibitor overcomes resistance to first‐ and second‐generation inhibitors in NSCLC

Yue Lü, Zhenzhen Fan, Sujie Zhu, +26

EMBO Molecular Medicine

Health SciencesMedicineNew Alk InhibitorMechanism Of ActionSecond‐generation Inhibitors +8

Targeting PRMT1-mediated SRSF1 methylation to suppress oncogenic exon inclusion events and breast tumorigenesis

Wenjuan Li, Ying Huang, Yi-an Lin, +10

Cell Reports

A Kind of Design Schema of Wireless Smart Water Meter Reading System Based on Zigbee Technology

Baoding Zhang, Liu Jialei

Smart SensorEngineeringIntelligent SensorSensorsAdvanced Metering Infrastructure +12

Promoting Cardiac Repair through Simple Engineering of Nanoparticles with Exclusive Targeting Capability toward Myocardial Reperfusion Injury by Thermal Resistant Microfluidic Platform

Zehua Liu, Wenhua Lian, Qiang Long, +15

Advanced Functional Materials

NanoparticlesExclusive Targeting CapabilityHeart FailureNanotherapeuticsEngineering +20