András N. Spaan

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

Paul Bastard, Lindsey B. Rosen, Qian Zhang et al. · Science · 2020 · 2.8K citations · Full text

Viral Diagnostics, Immunodeficiencies, Viral Immunity +19

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Paul Bastard, Adrian Gervais, Tom Le Voyer et al. · Science Immunology · 2021 · 600 citations · Full text

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19

Takaki Asano, Bertrand Boisson, Fanny Onodi et al. · Science Immunology · 2021 · 410 citations · Full text

The Staphylococcal Toxin Panton-Valentine Leukocidin Targets Human C5a Receptors

András N. Spaan, Thomas Henry, Willemien J. M. van Rooijen et al. · Cell Host & Microbe · 2013 · 289 citations · Full text

Medicine, Immunology, Immunopathology +1

A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection

Jean‐Laurent Casanova, Helen C. Su, Laurent Abel et al. · Cell · 2020 · 231 citations · Full text