mRNA Vaccines Against SARS‐CoV‐2 Variants Delivered by Lipid Nanoparticles Based on Novel Ionizable Lipids

Kepan Chen, Na Fan, Hai Huang, +11

Advanced Functional Materials

CRISPR-Cas13 Inhibitors Block RNA Editing in Bacteria and Mammalian Cells

Ping Lin, Shugang Qin, Qinqin Pu, +12

Molecular Cell

Off-target EffectMedicineNatural SciencesMolecular BiologyGenetic Engineering +7

Manganese-coordinated mRNA vaccines with enhanced mRNA expression and immunogenicity induce robust immune responses against SARS-CoV-2 variants

Na Fan, Kepan Chen, Rong Zhu, +15

Science Advances

VaccinationRobust Immune ResponsesSars-cov-2 VariantsManganese-coordinated Mrna VaccinesVaccine Development +13

Gut Microbiota Regulate Gut–Lung Axis Inflammatory Responses by Mediating ILC2 Compartmental Migration

Qinqin Pu, Ping Lin, Pan Gao, +10

The Journal of Immunology

High-throughput screen reveals sRNAs regulating crRNA biogenesis by targeting CRISPR leader to repress Rho termination

Ping Lin, Qinqin Pu, Qun Wu, +12

Nature Communications

Engineered Bacteriophages Containing Anti-CRISPR Suppress Infection of Antibiotic-Resistant P. aeruginosa

Shugang Qin, Yongan Liu, Yuting Chen, +15

Microbiology Spectrum

Identification of cGAS as an innate immune sensor of extracellular bacterium Pseudomonas aeruginosa

Chuan‐Min Zhou, Biao Wang, Qun Wu, +5

iScience

Small-Molecule Inhibitor of 8-Oxoguanine DNA Glycosylase 1 Regulates Inflammatory Responses during <i>Pseudomonas aeruginosa</i> Infection

Shugang Qin, Ping Lin, Qun Wu, +14

The Journal of Immunology

Microbial and genetic-based framework identifies drug targets in inflammatory bowel disease

Zhihan Wang, Kai Guo, Pan Gao, +8

Theranostics

Sodium alginate coating simultaneously increases the biosafety and immunotherapeutic activity of the cationic mRNA nanovaccine

Xing Duan, Yi Zhang, Na Fan, +8

Acta Pharmaceutica Sinica B