Kepan Chen

Artificial intelligence-driven rational design of ionizable lipids for mRNA delivery

Wei Wang, Kepan Chen, Ting Jiang et al. · Nature Communications · 2024 · 113 citations · Full text

mRNA Vaccines Against SARS‐CoV‐2 Variants Delivered by Lipid Nanoparticles Based on Novel Ionizable Lipids

Kepan Chen, Na Fan, Hai Huang et al. · Advanced Functional Materials · 2022 · 102 citations · Full text

Manganese-coordinated mRNA vaccines with enhanced mRNA expression and immunogenicity induce robust immune responses against SARS-CoV-2 variants

Na Fan, Kepan Chen, Rong Zhu et al. · Science Advances · 2022 · 90 citations · Full text

Vaccination, Robust Immune Responses, Sars-cov-2 Variants +15

Lipid Nanoparticle Delivery System for mRNA Encoding B7H3‐redirected Bispecific Antibody Displays Potent Antitumor Effects on Malignant Tumors

Cheng Huang, Xing Duan, Jichao Wang et al. · Advanced Science · 2022 · 52 citations · Full text

Nanotherapeutics, Engineering, Immunology +23

A lipid-based LMP2-mRNA vaccine to treat nasopharyngeal carcinoma

Xing Duan, Xingchen Peng, Zhaohui Jin et al. · Nano Research · 2023 · 35 citations · Full text