Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxia

Yuanyuan Wang, Changsen Bai, Yuxia Ruan, +5

Nature Communications

Glutamine NitrogenGlutamine CarbonRedox BiologyTumor BiologyOxidative Stress +19

De novo pyrimidine biosynthetic complexes support cancer cell proliferation and ferroptosis defence

Chuanzhen Yang, Yiliang Zhao, Liao Wang, +9

Nature Cell Biology

BiochemistryMedicineNatural SciencesBioconjugationMolecular Biology +4

Association between dopaminergic genes (SLC6A3 and DRD2) and stuttering among Han Chinese

Jie Lan, Manshu Song, Chun-Hui Pan, +9

Journal of Human Genetics

Genetic DisorderGeneticsSpeech Fluency DisorderDopaminergic GenesHan Chinese +4

Inhibiting both proline biosynthesis and lipogenesis synergistically suppresses tumor growth

Miao Liu, Yuanyuan Wang, Chuanzhen Yang, +7

The Journal of Experimental Medicine

Proline BiosynthesisCell ProliferationMetabolic RemodelingChemical BiologyMetabolic Model +19

Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress

Ronghui Yang, Chuanzhen Yang, Lingdi Ma, +6

Nature Communications

Hypoxia-induced downregulation of PGK1 crotonylation promotes tumorigenesis by coordinating glycolysis and the TCA cycle

Zihao Guo, Yang Zhang, Haoyue Wang, +10

Nature Communications

hCLP46 regulates U937 cell proliferation via Notch signaling pathway

Wenzhan Ma, Jie Du, Qiaoyun Chu, +4

Biochemical and Biophysical Research Communications

Signaling PathwayCell RegulationMolecular RegulationU937 Cell ProliferationMedicine +2

Overexpression of Human CAP10-Like Protein 46 KD in T-Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia

Youxin Wang, Naibai Chang, Tian Zhang, +6

Genetic Testing and Molecular Biomarkers

Repurposing a tricyclic antidepressant in tumor and metabolism disease treatment through fatty acid uptake inhibition

Qiaoyun Chu, Jing An, Ping Liu, +6

The Journal of Experimental Medicine

Stearate‐derived very long‐chain fatty acids are indispensable to tumor growth

Qiaoyun Chu, Ping Liu, Yihan Song, +6

The EMBO Journal

Lipid SynthesisBiochemistryOmega-3 Fatty AcidMedicineLipid Nutrition +7