H. Charles Manning

Cell-programmed nutrient partitioning in the tumour microenvironment

Bradley I. Reinfeld, Matthew Z. Madden, Melissa M. Wolf et al. · Nature · 2021 · 942 citations · Full text

Medicine, Biological Microenvironments, Cell Proliferation +6

Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models

M. Schulte, Allie Fu, Ping Zhao et al. · Nature Medicine · 2018 · 470 citations · Full text

Tumor Biology, Drug Targeting, Preclinical Models +10

Selective glutamine metabolism inhibition in tumor cells improves antitumor T lymphocyte activity in triple-negative breast cancer

Deanna N. Edwards, Verra M. Ngwa, Ariel Raybuck et al. · Journal of Clinical Investigation · 2020 · 329 citations · Full text

Breast Oncology, Immunology, Tumor Cells +18

Evaluation of CD44 and CD133 as cancer stem cell markers for colorectal cancer

Chunxia Wang, Jingping Xie, Jiasong Guo et al. · Oncology Reports · 2012 · 167 citations · Full text

A Kinome-Wide Screen Identifies the Insulin/IGF-I Receptor Pathway as a Mechanism of Escape from Hormone Dependence in Breast Cancer

Emily M. Fox, Todd W. Miller, Justin M. Balko et al. · Cancer Research · 2011 · 154 citations · Full text

Breast Oncology, Human Growth, Kinome-wide Screen +22