Ángela Macia

Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation

Charles A. Thomas, Leon Tejwani, Cleber A. Trujillo et al. · Cell stem cell · 2017 · 332 citations · Full text

Inflammation, Autoimmune Disease, Trex1-dependent Autoimmune Disease +11

Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells

Nicole G. Coufal, José L. García-Pérez, Grace E. Peng et al. · Proceedings of the National Academy of Sciences · 2011 · 227 citations

Neurogenomics, Genetics, Genomic Mechanism +26

LINE-1 Evasion of Epigenetic Repression in Humans

Francisco J. Sánchez‐Luque, Marie-Jeanne H.C. Kempen, Patricia Gerdes et al. · Molecular Cell · 2019 · 174 citations · Full text

Chromatin, Epigenetic Change, Genetics +5

Engineered LINE-1 retrotransposition in nondividing human neurons

Ángela Macia, Thomas J. Widmann, Sara R. Heras et al. · Genome Research · 2016 · 161 citations · Full text

Adult Stem Cell, Neurotransmission, Line-1 Retrotransposition +17

Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility

Silke Wissing, Martín Muñoz-López, Ángela Macia et al. · Human Molecular Genetics · 2011 · 148 citations · Full text