Regulation of therapeutic hypothermia on inflammatory cytokines, microglia polarization, migration and functional recovery after ischemic stroke in mice

Jin Hwan Lee, Zheng Wei, Wenyuan Cao, +6

Neurobiology of Disease

ImmunologyMicroglia PolarizationCerebral Vascular RegulationNeuroinflammationInflammation +17

Vitamin D Prevents Hypoxia/Reoxygenation-Induced Blood-Brain Barrier Disruption via Vitamin D Receptor-Mediated NF-kB Signaling Pathways

Soonmi Won, Iqbal Sayeed, Bethany L. Peterson, +3

PLoS ONE

Lipid PeroxidationBlood-brain Barrier IntegrityCerebral Vascular RegulationOxidative StressBrain Injury +19

Progesterone Attenuates Hemorrhagic Transformation after Delayed tPA Treatment in an Experimental Model of Stroke in Rats: Involvement of the VEGF–MMP Pathway

Soonmi Won, Jin Hwan Lee, Bushra Wali, +2

Journal of Cerebral Blood Flow & Metabolism

Oxidative StressCerebral Vascular RegulationInflammationThrombosisNeurovascular Disease +18

Progesterone in experimental permanent stroke: a dose-response and therapeutic time-window study

Bushra Wali, Tauheed Ishrat, Soonmi Won, +2

Brain

Therapeutic Time-window StudyHormonal ContraceptiveProgesterone GroupProgesterone Dose-responseCerebrovascular Disease +25

Recombinant tissue plasminogen activator promotes, and progesterone attenuates, microglia/macrophage M1 polarization and recruitment of microglia after MCAO stroke in rats

Soonmi Won, Jae‐Kyung Lee, Donald G. Stein

Brain Behavior and Immunity

InflammationMicroglia/macrophage M1 PolarizationMedicineImmunologyProgesterone Attenuates +10

Sex-related differences in effects of progesterone following neonatal hypoxic brain injury

Bethany L. Peterson, Soonmi Won, Rastafa I. Geddes, +2

Behavioural Brain Research

Brain InjuryNeuroscienceNeurologySex-related DifferencesFetal Neurodevelopment +4

Neonatal inflammatory pain and systemic inflammatory responses as possible environmental factors in the development of autism spectrum disorder of juvenile rats

Jin Hwan Lee, Alyssa R. Espinera, Dongdong Chen, +7

Journal of Neuroinflammation

GSK-3β Inhibition Induced Neuroprotection, Regeneration, and Functional Recovery after Intracerebral Hemorrhagic Stroke

Yingying Zhao, Zheng Wei, James Ya Zhang, +6

Cell Transplantation

Improved Therapeutic Benefits by Combining Physical Cooling With Pharmacological Hypothermia After Severe Stroke in Rats

Jin Hwan Lee, Ling Wei, Xiaohuan Gu, +4

Stroke

Progesterone protects endothelial cells after cerebrovascular occlusion by decreasing MCP-1- and CXCL1-mediated macrophage infiltration

Ebony Washington Remus, Iqbal Sayeed, Soonmi Won, +2

Experimental Neurology

InflammationCytokineAngiogenesisEndothelial CellsImmunology +10