Nadia Brügger

Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton’s Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases

Richard D. Caldwell, Hui Qiu, Ben Askew et al. · Journal of Medicinal Chemistry · 2019 · 140 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Discovery, Structure–Activity Relationship, and Antiparkinsonian Effect of a Potent and Brain-Penetrant Chemical Series of Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4

Delphine Charvin, Vincent Pomel, Millán Ortiz et al. · Journal of Medicinal Chemistry · 2017 · 43 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Identification, synthesis, and biological evaluation of novel pyrazoles as low molecular weight luteinizing hormone receptor agonists

Catherine Jorand‐Lebrun, Bill Brondyk, Jing‐Jer Lin et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Reinforcing the supply chain of umifenovir and other antiviral drugs with retrosynthetic software

Yingfu Lin, Zirong Zhang, Babak Mahjour et al. · Nature Communications · 2021 · 27 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

Synthesis and evaluation of novel pyrazolidinone analogs of PGE2 as EP2 and EP4 receptors agonists

Zhong Zhao, Gian Luca Araldi, Yufang Xiao et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 18 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8