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Aravind Subramanian, Rajiv Narayan, Steven M. Corsello, +53

Cell

Network ScienceEngineeringData ScienceEdge ComputingComputer Engineering +10

Genetic and transcriptional evolution alters cancer cell line drug response

Uri Ben‐David, Benjamin A. Siranosian, Gavin Ha, +27

Nature

Tumor HeterogeneityMedicineOncogenic AgentCancer GenomicsLine Drug Response +7

Discovering the anticancer potential of non-oncology drugs by systematic viability profiling

Steven M. Corsello, Rohith T. Nagari, Ryan D. Spangler, +35

Nature Cancer

Tumor BiologySystematic Viability ProfilingMedicineCancer ManagementPharmacology +10

Patient-derived xenografts undergo mouse-specific tumor evolution

Uri Ben‐David, Gavin Ha, Yuen‐Yi Tseng, +8

Nature Genetics

Lineage PlasticityXenotransplantationTumor HeterogeneityMedicineRadiation Oncology +2

Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer

Jens G. Lohr, Viktor A. Adalsteinsson, Kristian Cibulskis, +35

Nature Biotechnology

High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines

Channing Yu, Aristotle M. Mannan, Griselda M. Yvone, +18

Nature Biotechnology

BioinformaticsFunctional GenomicsEngineeringTumor HeterogeneityMedicine +11

A High-Throughput Chromatin Immunoprecipitation Approach Reveals Principles of Dynamic Gene Regulation in Mammals

Manuel Garber, Nir Yosef, Alon Goren, +24

Molecular Cell

ChromatinChromatin RemodelingGeneticsDynamic Gene RegulationGene Expression +7

Points of view: Color blindness

Bang Wong

Nature Methods

Cognitive ScienceVisual CognitionVisual ImpairmentSocial SciencesColor Blindness

Tight Coordination of Protein Translation and HSF1 Activation Supports the Anabolic Malignant State

Sandro Santagata, Marc L. Mendillo, Yun‐Chi Tang, +12

Science

Molecular BiologyProtein TranslationMetabolic RemodelingTumor BiologyTranscriptional Regulation +17

High-throughput Phenotyping of Lung Cancer Somatic Mutations

Alice H. Berger, Angela N. Brooks, Xiaoyun Wu, +28

Cancer Cell

Somatic VariantTumor HeterogeneityMedicineGeneticsHigh-throughput Phenotyping +3