Costantino Pitzalis

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry

Fan Zhang, Kevin Wei, Kamil Slowikowski et al. · Nature Immunology · 2019 · 1.3K citations · Full text

Immunology, Inflammatory Arthritis, Inflammation +16

Lactate Regulates Metabolic and Pro-inflammatory Circuits in Control of T Cell Migration and Effector Functions

Robert Haas, Joanne Smith, Vidalba Rocher-Ros et al. · PLoS Biology · 2015 · 732 citations · Full text

T-regulatory Cell, Immunology, Lactate Regulates Metabolic +22

Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis

Stefano Alivernini, Lucy MacDonald, Aziza Elmesmari et al. · Nature Medicine · 2020 · 643 citations

Inflammation, Rheumatology, Rheumatoid Disorder +10

Ectopic Lymphoid Structures Support Ongoing Production of Class-Switched Autoantibodies in Rheumatoid Synovium

Frances Humby, Antonio Manzo, Stephen Kelly et al. · PLoS Medicine · 2009 · 526 citations · Full text

Notch signalling drives synovial fibroblast identity and arthritis pathology

Kevin Wei, Ilya Korsunsky, Jennifer L. Marshall et al. · Nature · 2020 · 494 citations · Full text

Inflammation, Rheumatology, Rheumatoid Disorder +10