K. Mark Parnell

The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure

Ahmad A. Cluntun, Rachit Badolia, Sandra Lettlová et al. · Cell Metabolism · 2020 · 305 citations · Full text

Cardiac Muscle, Cardiomyopathy, Heart Failure +6

Substrate-assisted catalysis of peptide bond formation by the ribosome

Joshua S. Weinger, K. Mark Parnell, Silke Dorner et al. · Nature Structural & Molecular Biology · 2004 · 273 citations

Biochemistry, Protein Folding, Peptide Synthesis +3

Pharmacologic Activation of PKM2 Slows Lung Tumor Xenograft Growth

K. Mark Parnell, Jason M. Foulks, Rebecca N. Nix et al. · Molecular Cancer Therapeutics · 2013 · 69 citations

Monocarboxylate transporter antagonism reveals metabolic vulnerabilities of viral-driven lymphomas

Emmanuela N. Bonglack, Joshua E. Messinger, Jana M. Cable et al. · Proceedings of the National Academy of Sciences · 2021 · 58 citations · Full text

Discovery of 3-(trifluoromethyl)-1H-pyrazole-5-carboxamide activators of the M2 isoform of pyruvate kinase (PKM2)

Yong Xu, Xiaohui Liu, Michael A. Saunders et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 49 citations

Pharmaceutical Chemistry, Biochemistry, Medicine +8