Margaret J. Currie

The angiogenic switch for vascular endothelial growth factor (VEGF)‐A, VEGF‐B, VEGF‐C, and VEGF‐D in the adenoma–carcinoma sequence during colorectal cancer progression

Vickie Hanrahan, Margaret J. Currie, Sarah Gunningham et al. · The Journal of Pathology · 2003 · 237 citations · Full text

Angiogenesis, Adenoma–carcinoma Sequence, Vegf Angiogenic Switch +15

Low Ascorbate Levels Are Associated with Increased Hypoxia-Inducible Factor-1 Activity and an Aggressive Tumor Phenotype in Endometrial Cancer

Caroline Kuiper, Ilona G.M. Molenaar, Gabi U. Dachs et al. · Cancer Research · 2010 · 134 citations · Full text

Tumor Biology, Ascorbate Content, Aggressive Tumor Phenotype +15

Modulation of hypoxia-inducible factor-1 alpha in cultured primary cells by intracellular ascorbate

Margret C.M. Vissers, Sarah Gunningham, Mary J. Morrison et al. · Free Radical Biology and Medicine · 2006 · 129 citations

Inflammation, Cultured Primary Cells, Hypoxia-inducible Factor-1 Alpha +12

Intracellular ascorbate enhances hypoxia-inducible factor (HIF)-hydroxylase activity and preferentially suppresses the HIF-1 transcriptional response

Caroline Kuiper, Gabi U. Dachs, Margaret J. Currie et al. · Free Radical Biology and Medicine · 2014 · 123 citations

Transcriptional Regulation, Redox Regulator, Physiology +11

The short form of the alternatively spliced flt-4 but not its ligand vascular endothelial growth factor C is related to lymph node metastasis in human breast cancers.

Sarah Gunningham, Margaret J. Currie, Bridget A. Robinson et al. · PubMed · 2000 · 108 citations

Breast Oncology, Immunology, Pathology +17