Matthew AH Parson

Oncogenic mutations of PIK3CA lead to increased membrane recruitment driven by reorientation of the ABD, p85 and C-terminus

Meredith L. Jenkins, Harish Ranga-Prasad, Matthew AH Parson et al. · Nature Communications · 2023 · 71 citations · Full text

Palmitoylation targets the calcineurin phosphatase to the phosphatidylinositol 4-kinase complex at the plasma membrane

Idil Ulengin-Talkish, Matthew AH Parson, Meredith L. Jenkins et al. · Nature Communications · 2021 · 44 citations · Full text

A previously uncharacterized O-glycopeptidase from Akkermansia muciniphila requires the Tn-antigen for cleavage of the peptide bond

Brendon J Medley, Leif Leclaire, Nicole Thompson et al. · Journal of Biological Chemistry · 2022 · 27 citations · Full text

ATP-competitive and allosteric inhibitors induce differential conformational changes at the autoinhibitory interface of Akt1

Alexandria L Shaw, Matthew AH Parson, Linda Truebestein et al. · Structure · 2023 · 21 citations

Protein Function, Signal Transduction, Molecular Physiology +14

Biochemical Insight into Novel Rab-GEF Activity of the Mammalian TRAPPIII Complex

Noah J Harris, Meredith L. Jenkins, Udit Dalwadi et al. · Journal of Molecular Biology · 2021 · 17 citations

Mammalian Trappiii Complex, Signal Transduction, Novel Rab-gef Activity +10